25 replies to this topic

[Melchoire]

SN: Opiates are seriously potentiated when you keep the enzyme CYP 450 2D6 busy. So for example, I'd take about ~50mg of diphenhydramine (benadryl) about half an hour prior to dosing with opiates. You will clearly notice an increase in peak plasma levels and also will notice quite an extended duration of effects. This is caused as essentially the enzyme is too busy breaking up the benadryl to start metabolizing the opiates. This will also reduce the itchiness that opiates cause as diphenhydramine is an anti-histamine and the itchiness is actually caused from histamine release...

Brilliant! I always wondered what caused that itchiness. It's such a nuisance when you're trying to sleep but you keep having to scratch something on your body.

I mention the above because what otherwise may be considered minor factors can actually be the culprit. Of course, there is always another possibility; the difference is solely psychological. When you say that he feels it for the whole day and you only feel it for 4-5 hours, you are implying that the difference is based upon individual observation. He may have a more keen sense of disturbance in his normal bodily function...

That's true. We both use it as a study aid. I guess he defines it as how long he can stay focused before he gives up and does something else.

But FYI, amphetamine salts consumed orally will normally only last 4-6 hours before returning almost entirely to baseline. (Minus any time with off-baseline cravings, side effects, come downs, etc.) So your range actually seems to be more appropriate... They do make Adderall XR here in the states which is just extended release amphetamine salts. Essentially, they are solidified in these tiny little balls and contained within a capsule. These tiny little balls each have varying amounts of coating so that some beads will be dissolved in your stomach and absorbed nearly immediately while others will take 6-8 hours before they are ever absorbed.... Leading to a prolonged experience.

Hah! That's exactly what I got from my friend. It's a 30mg clear capsule with a bunch of orange and yellow beads. I opened the capsule and ate half of beads. Still lasting me too(took it 4 hours ago). I just got finished dinner after I got home and I'm gonna keep working through the night.

P.s. It's also possible that it's just a difference in body weight... But frankly, you're time frame appears closer to the "norm" than his does.

Yeh, I was doubtful about it too. But the point was that he was high for much much longer than me.


Anyway, thanks a lot for a lengthy thorough response....you really know your shit. =P

Edit: I had to really force down my dinner. This stuff really suppresses your appetite.

No study aids- I am smart.

Oh yeah? Say something smart!

Never even heard of these pills before for studying, normally I just take a energy drink or something

Caffeine makes me piss like a race horse. It's counter-productive to my studying

Update: I underestimated how strong the adderall's dosage was. I took 20mg and couldn't fall asleep at all. On the plus side I got a good amount of work done but I feel really dehydrated, my body keeps flushing all the water I drink and I have no urge to eat anything at all. Will have to take much less next time.