I'm currently reading One Piece, Naruto, Bleach, Fairy Tail, Claymore, New Prince of Tennis, GTO: Shonan 14 days and was reading Yakitate Japan (even though the author seems to have gone AWOL for months)
Best series that I've ever watched in terms of storyline/action are Fullmetal Alchemist: Brotherhood and the Darker Than Black series.
My comedy favorites would be School Rumble followed by Toradora.